Clinical studies looking for participants
What's being studied, where it's happening and whether it's recruiting. Start with your state and recruitment status, then open a few studies. Your care team decides eligibility.
What the phases mean
Phase 1 studies test safety in a small group, often with increasing doses. Phase 2 looks for signs of benefit and the right dose. Phase 3 compares the treatment with placebo in larger numbers to confirm benefit; these are the studies that lead to approval. Expanded access programs provide an investigational drug outside a trial to people who can't join one. Observational studies and registries collect information and samples without testing a treatment, and some can be done from home.
Platform trials like the HEALEY ALS Platform Trial test several drugs at once with a shared placebo group, so more participants get an active drug. Enrollment opens and closes by regimen.
Questions to ask the study team
- What is being tested, and what's the chance I get a placebo?
- Is there an open-label extension where everyone gets the drug?
- How many visits, how far, and are travel and lodging reimbursed?
- Can I keep taking riluzole, edaravone or other medications?
- Will joining this study keep me out of other trials?
- What happens to my care when the study ends?
See every ALS study, worldwide
This page is a dated snapshot of the registry. New studies post every week, so check the live sources too.
- ClinicalTrials.gov ↗The official U.S. registry. Every study here links to its record.
- ALS Trial Navigator (ALS TDI & NEALS) ↗Guided questions, filters and a global map, updated daily.
- SAVA trial guide (Everything ALS & NEALS) ↗Plain-language help exploring studies that match your situation.
- ALS TDI: Let Us Help ↗Talk with ALS TDI staff about research and trials. NEALS also answers questions at alstrials@neals.org.